Doccol是一(yi)家美國(guo)生(sheng)物技術公司，從(cong)解決(jue)生(sheng)物研(yan)究(jiu)(jiu)(jiu)中(zhong)(zhong)(zhong)的(de)(de)(de)實際問題開始。2004年，Doccol發(fa)現(xian)了(le)(le)實驗(yan)性卒中(zhong)(zhong)(zhong)研(yan)究(jiu)(jiu)(jiu)的(de)(de)(de)關鍵問題之(zhi)一(yi)是卒中(zhong)(zhong)(zhong)模(mo)(mo)(mo)型(xing)(xing)的(de)(de)(de)質量不一(yi)致(zhi)(zhi)，因(yin)此通(tong)過(guo)提(ti)供(gong)(gong)標(biao)準化的(de)(de)(de)封(feng)堵器(qi)(qi)，即(ji)硅(gui)橡膠(jiao)涂(tu)層(ceng)單絲，用(yong)(yong)于大腦中(zhong)(zhong)(zhong)動脈(mo)閉(bi)塞（MCAO），為(wei)此提(ti)供(gong)(gong)了(le)(le)解決(jue)方案。這(zhe)些MCAO封(feng)堵器(qi)(qi)深受中(zhong)(zhong)(zhong)風科(ke)研(yan)人員的(de)(de)(de)喜愛，并(bing)被命名為(wei)“MCAO縫合線(xian)(xian)"。 我(wo)(wo)們精致(zhi)(zhi)的(de)(de)(de)硅(gui)橡膠(jiao)涂(tu)層(ceng)單絲是專門為(wei)誘(you)導(dao)MCAO腔內燈(deng)絲模(mo)(mo)(mo)型(xing)(xing)而設計(ji)制造的(de)(de)(de)，該模(mo)(mo)(mo)型(xing)(xing)已被廣泛用(yong)(yong)于體(ti)內實驗(yan)性腦卒中(zhong)(zhong)(zhong)研(yan)究(jiu)(jiu)(jiu)。使(shi)(shi)用(yong)(yong) Doccol MCAO 縫合線(xian)(xian)誘(you)導(dao)卒中(zhong)(zhong)(zhong)模(mo)(mo)(mo)型(xing)(xing)將通(tong)過(guo)減少不全部閉(bi)塞和顱內出(chu)血的(de)(de)(de)發(fa)生(sheng)來提(ti)高(gao)模(mo)(mo)(mo)型(xing)(xing)質量。使(shi)(shi)用(yong)(yong)Doccol MCAO縫合線(xian)(xian)，您(nin)將能夠實現(xian)高(gao)度一(yi)致(zhi)(zhi)的(de)(de)(de)梗死(si)以(yi)及低死(si)亡率(lv)。除了(le)(le)認可的(de)(de)(de)產品(pin)質量外，Doccol還為(wei)MCAO縫合線(xian)(xian)提(ti)供(gong)(gong)了(le)(le)種(zhong)類繁多的(de)(de)(de)縫合線(xian)(xian)，旨在滿足中(zhong)(zhong)(zhong)風研(yan)究(jiu)(jiu)(jiu)人員的(de)(de)(de)各種(zhong)需(xu)求。多年來，我(wo)(wo)們的(de)(de)(de)MCAO縫合線(xian)(xian)一(yi)直被中(zhong)(zhong)(zhong)風研(yan)究(jiu)(jiu)(jiu)人員優選用(yong)(yong)于誘(you)導(dao)中(zhong)(zhong)(zhong)風模(mo)(mo)(mo)型(xing)(xing)。據報道，使(shi)(shi)用(yong)(yong)Doccol MCAO縫合線(xian)(xian)誘(you)導(dao)MCAO模(mo)(mo)(mo)型(xing)(xing)能夠將梗死(si)體(ti)積(ji)的(de)(de)(de)標(biao)準偏差(cha)降低到其(qi)相(xiang)應平均值的(de)(de)(de)5%; 這(zhe)種(zhong)建模(mo)(mo)(mo)方法正(zheng)在成(cheng)為(wei)確保MCAO模(mo)(mo)(mo)型(xing)(xing)最高(gao)質量的(de)(de)(de)新標(biao)準。欲了(le)(le)解更多信(xin)息(xi)，中(zhong)(zhong)(zhong)國(guo)客戶請聯系(xi)美國(guo)Doccol在中(zhong)(zhong)(zhong)國(guo)的(de)(de)(de)總代理靶點科(ke)技。

2010年，Doccol注意到大(da)多數實驗室進行的(de)(de)(de)微(wei)血管(guan)(guan)導管(guan)(guan)插入(ru)術對于血液檢(jian)測(ce)和(he)(he)(he)藥物輸送(song)(song)(song)都不方便。這些“微(wei)導管(guan)(guan)"有(you)一個需(xu)要針頭連(lian)接的(de)(de)(de)過渡管(guan)(guan)，當壓力(li)高時可能會斷裂，并且(qie)可能會意外刺入(ru)操作員的(de)(de)(de)手指，然后才能連(lian)接到合成器。這些導管(guan)(guan)也有(you)很大(da)的(de)(de)(de)內(nei)(nei)部(bu)(bu)容積，必須處理才能輸送(song)(song)(song)藥物。Doccol 提(ti)供專門設計的(de)(de)(de)微(wei)導管(guan)(guan)，用于提(ti)高嚙齒(chi)動物血液采樣、藥物輸送(song)(song)(song)、小(xiao)流(liu)速液體(ti)轉移和(he)(he)(he)生(sheng)理監測(ce)的(de)(de)(de)性能、質量和(he)(he)(he)生(sheng)產率(lv)，其中需(xu)要侵入(ru)性血管(guan)(guan)通路(lu)。我們的(de)(de)(de)微(wei)導管(guan)(guan)連(lian)接到工業標準的(de)(de)(de)魯爾(er)鎖或旋塞閥，因此消除了過渡管(guan)(guan)和(he)(he)(he)針頭連(lian)接，也大(da)大(da)減(jian)少了內(nei)(nei)部(bu)(bu)體(ti)積。Doccol 為(wei)所有(you)常見部(bu)(bu)位的(de)(de)(de)血管(guan)(guan)插管(guan)(guan)提(ti)供了足夠的(de)(de)(de)微(wei)導管(guan)(guan)選擇，例如尾靜脈、股靜脈、頸靜脈和(he)(he)(he)臂(bei)靜脈和(he)(he)(he)動脈，以及頸靜脈。

在Doccol多(duo)年來致力于(yu)中(zhong)風(feng)研(yan)究期間，Doccol 還開(kai)始提供(gong)精(jing)心(xin)挑選(xuan)的基本顯微手術工(gong)具(ju)(ju)和設備(bei)，并于(yu) 2019 年開(kai)發了其(qi)不同的基于(yu) Arduino 的 PID 溫(wen)度控(kong)制(zhi)器。這些(xie)工(gong)具(ju)(ju)和設備(bei)可確保您(nin)的實驗性中(zhong)風(feng)研(yan)究具(ju)(ju)有(you)高(gao)質(zhi)量和高(gao)生產率。

Doccol is a biotech company that started from solving real problems in biological research. In 2004, Doccol identified one of the key problems in experimental stroke research is the inconsistent quality of stroke models, and thence provided a solution for this by offerring standardized occluders, the silicone rubber-coated monofilaments,  for middle cerebral artery occlusion (MCAO). Those MCAO occluders  were liked very much by stroke reaearchers and given the name "MCAO sutures".  Our delicate silicone rubber-coated monofilaments are specially designed and manufactured for inducing the intraluminal filament model of MCAO, which has been widely used for in vivo experimental stroke studies. Using Doccol MCAO sutures for inducing stroke models will improve your model quality by reducing the occurrence of both the incomplete occlusion and the intracranial bleeding. With Doccol MCAO sutures, you will be able to achieve a highly consistent infarct as well as a low mortality rate. In addition to the super product quality, Doccol provides MCAO sutures with a great variety that was designed to meet the diverse demand from stroke investigators. For many years our MCAO sutures have been preferably selected by stroke investigators for inducing stroke models. Using Doccol MCAO sutures for inducing MCAO models has been reported to be able to reduce the standard deviation to 5% of its corresponding mean value as for infarction volume; and this modeling method is becoming a methodological new standard for ensuring the highest quality of MCAO models. For more information please read Doccol Made a Difference in Stroke Modeling.

In 2010, Doccol noticed that microvascular catheterization procedures performed in most laboratories are inconvinient for both blood testing and drug delivery. Those "microcatheters" have a transition tubing requiring a needle connection, which may break when pressure is high, and may accidentally puncture into the operator's finger, before it can be connected to a synringe. These catheters also have a large inner volume that has to be dealt with for drug delivery. Doccol offerred specially designed microcatheters for improving performance, quality and productivity in rodent blood sampling, drug delivery, small flow rate liquid transferring, and physiological monitoring, in which invasive vascular access is necessary. Our microcatheters are permanently connected to an industrial standard Luer lock or stopcock, therefore, eliminated the transitional tubing and needle connection and also dramatically reduced inner volume. Doccol provides sufficient choices of micro catheters for vascular cannulation in all common locations, such as the tail, femoral, carotid, and brachial veins and arteries, and also the jugular veins.

During years of our dedicated services in stroke research, Doccol also started to provide our carefully-selected essential microsurgical tools and devices, and in 2019 Doccol developed its unique Arduino-based PID temperature controllers. These essential tools and devices ensure your experimental stroke research with high quality and high productivity.

靶點科技（北京）有(you)限(xian)公司(si)（Target Technology (Beijing) Co.,Ltd.），成(cheng)立(li)于(yu)2016年，是由(you)一群來自歐洲荷蘭(lan)的留學海(hai)歸和高校(xiao)及研究所博士人員創辦的生物高科技公司(si)。公司(si)基于(yu)四個平臺技術TargoSome^®（脂質(zhi)體靶向技術），TargoChem^®（化合物靶向技術(shu)），TargoAnti^®（抗體靶向技術）和TargoNano^®（納米靶(ba)向技術），研(yan)發了(le)靶(ba)向細胞的遞(di)送系統。

公司注重轉化(hua)醫學，強化(hua)“Bench-to-Bedside"的基(ji)礎產品開發。目前(qian)，靶點科技已經成(cheng)為單核巨噬細胞(bao)系(xi)統(tong)研(yan)究領域的(de)樹立良好口碑，能夠給研(yan)究人(ren)員提供(gong)各(ge)種模擬人(ren)類疾病的(de)動(dong)物模型的(de)制備，公司團(tuan)隊對單核巨噬細胞(bao)系(xi)統(tong)有著深刻的(de)認識(shi)和理解，從標記，分離，富集(ji)，純化，培養(yang)和細胞(bao)清除，形態識(shi)別等提供(gong)一整(zheng)套綜(zong)合解決方案(an)。

基于對靶點科技（北京）有限公司的認同，自2022年11月29日期，靶點科技被美國Doccol公司授權為中國總代理。客戶通過靶點科技購買美國Doccol公司的產品，質量可靠，渠道合法，售后無憂。大(da)腦中動(dong)脈阻塞(MCAO)造模是研(yan)究缺血(xue)性腦卒中(zhong)的經典動物模型，Doccol是MCAO造模國際廣泛使(shi)用的栓線(xian)品牌，文獻(xian)數以萬計(ji)。

靶點科技(ji)始終秉承“Bench to Bedside"的出發點，“專(zhuan)業⁺專(zhuan)注⁺"的(de)服務(wu)宗旨(zhi)，以“Hit Your Target^®"為目標(biao)， 竭力為客戶提供“Proven and Published^®"的一(yi)攬子綜合解決方案，將為實現這一(yi)美好愿景而努力奮(fen)斗。